concept

methicillin-resistant Staphylococcus aureus (MRSA)

Also known as: MRSA, methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant Staphylococcus aureus

Facts (23)

Sources

Medicinal plants: bioactive compounds, biological activities ... frontiersin.org Frontiers in Immunology 20 facts

claimThe acetone extract from Smilax zeylanica leaves is used for the treatment of ulcers and targets methicillin-resistant Staphylococcus aureus (MRSA) by causing cellular membrane instability and disintegration through ionic/electrostatic interactions and deposition on the bilayer surface.

referenceAlgammal AM, Hetta HF, Elkelish A, Alkhalifah DH, Hozzein WN, Batiha GE, et al. published 'Methicillin-resistant Staphylococcus aureus (MRSA): One health perspective approach to the bacterium epidemiology, virulence factors, antibiotic-resistance, and zoonotic impact' in Infection and Drug Resistance in 2020.

claimThe acetone extract from cinnamon leaves is used for the treatment of throat and skin infections and targets methicillin-resistant Staphylococcus aureus (MRSA) by binding to hydrophobic groups in the bacterial membrane due to the extract's hydrophobicity.

claimThe acetone extract from Syzygium praecox leaves is used for the treatment of skin infections and targets methicillin-resistant Staphylococcus aureus (MRSA) through ionic/electrostatic interactions with the cell membrane.

referenceEl-Mahdy et al. (2023) examined the effect of resveratrol and curcumin on the gene expression of toxins produced by methicillin-resistant Staphylococcus aureus (MRSA).

claimThe global proliferation of methicillin- and vancomycin-resistant Staphylococcus aureus strains is making containment increasingly unfeasible, potentially reverting medical capabilities to the pre-antibiotic era.

claimThe chloroform extract from Andrographis paniculata (green chireta) exhibits activity against Methicillin-resistant Staphylococcus aureus (MRSA).

claimMethicillin-resistant Staphylococcus aureus (MRSA) resists β-lactam antibiotics, including methicillin, isoxazolyl penicillin, and cephalosporins, by acquiring the mecA gene, which produces penicillin-binding protein 2a to modify its target site.

claimThe amphipathic characteristics of coastal golden leaf and bark contribute to its antibacterial efficacy against multidrug-resistant (MDR) Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterobacter species, and methicillin-resistant Staphylococcus aureus (MRSA).

referenceThe article 'Understanding the fight against resistance: hospital-acquired methicillin-resistant Staphylococcus aureus vs community-acquired methicillin-resistant Staphylococcus aureus' was published in the journal Cureus in 2020.

referenceKhameneh et al. (2015) investigated the antibacterial activity and efflux pump inhibitory effect of co-loaded piperine and gentamicin nanoliposomes in methicillin-resistant Staphylococcus aureus.

claimYu et al. reported that berberine blocks the NorA efflux pump in methicillin-resistant Staphylococcus aureus (MRSA), which reverses resistance to ciprofloxacin.

claimMethicillin-resistant Staphylococcus aureus (MRSA) emerged and spread during the 1960s in correlation with the use of vancomycin.

claimResveratrol, derived from grapes, suppressed the synthesis of staphylococcal enterotoxins in methicillin-resistant Staphylococcus aureus (MRSA) (272).

referenceGajdács M published 'The continuing threat of methicillin-resistant Staphylococcus aureus' in the journal Antibiotics in 2019.

claimThe ethanol extract from orange jessamine leaves is used for the treatment of cardiovascular disorders and targets methicillin-resistant Staphylococcus aureus (MRSA) through the hydrophobicity of the extract.

claimThe methanol extract from stiff bottlebrush leaves exhibits activity against Methicillin-resistant Staphylococcus aureus (MRSA).

claimMethicillin-resistant Staphylococcus aureus (MRSA) is a prime example of a superbug that contributes substantially to mortality from drug-resistant infections.

referenceBoswihi SS and Udo EE published 'Methicillin-resistant Staphylococcus aureus: An update on the epidemiology, treatment options and infection control' in Current Medicine Research and Practice in 2018.

claimThe use of non-lactam antibiotics for treating Staphylococcus aureus infections has increased due to the rise of antibiotic-resistant bacteria, particularly methicillin-resistant Staphylococcus aureus (MRSA).

Medicinal plants and human health: a comprehensive review of ... link.springer.com Springer Nov 5, 2025 3 facts

referenceZhu X, Zhao P, Jiang L, and Qi Y published a study on sanguinarine-induced proteomic changes in methicillin-resistant Staphylococcus aureus in the journal Xenobiotica in 2025.

referenceBerberine-infused cryogels act as smart membranes that target Methicillin-resistant Staphylococcus aureus (MRSA) and Multidrug-resistant Escherichia coli (MDR E. coli) using molecular docking-guided targeting, as reported by Yildirim et al. in 2025.

measurementBerberine derived from Berberis vulgaris has a minimum inhibitory concentration (MIC) of 32–128 μg/mL against methicillin-resistant Staphylococcus aureus (MRSA) by impairing membrane potential and ATP production.