concept

melanoma

Also known as: melanomas, melanoma skin cancer

Facts (3)

Sources

Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Nature Mar 14, 2023 2 facts

claimMelanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation, as reported by Landsberg et al. in Nature (2012).

claimT cell-driven inflammatory stimuli in melanomas cause melanoma cells to transition between differentiated and dedifferentiated states, conferring resistance to adoptive cell transfer (ACT) therapy.

Precision Medicine and Targeted Cancer Therapy | RGA rgare.com RGA 1 fact

claimMelanoma and lymphoma generate robust immune responses and have shown consistent susceptibility to the action of checkpoint inhibitors.