concept

matrix metalloproteinases

Also known as: MMPs, matrix metalloproteinase system

Facts (10)

Sources
The Normal Menstrual Cycle and the Control of Ovulation - NCBI - NIH ncbi.nlm.nih.gov Feingold KR, Adler RA, Ahmed SF · National Center for Biotechnology Information Aug 5, 2018 4 facts
claimMatrix metalloproteinases and their tissue inhibitors show dynamic expression of mRNAs and proteins in the primate corpus luteum during the menstrual cycle, as reported in a 2002 study in Molecular Human Reproduction.
claimMatrix metalloproteinases are involved in the process of luteolysis.
claimThe matrix metalloproteinase (MMP) system regulates the regeneration and remodeling of uterine connective tissue.
referenceCurry T.E. Jr and Osteen K.G. published a paper titled 'Cyclic changes in the matrix metalloproteinase system in the ovary and uterus' in the journal Biology of Reproduction in 2001.
Chronic Inflammation - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov National Library of Medicine 2 facts
claimNeutrophils contain granules rich in lysozyme, matrix metalloproteinases, and myeloperoxidase, which are released onto foreign or self-antigens to facilitate their destruction.
claimNeutrophils are the most predominant cells during the acute phase of inflammation and contain granules rich in lysozyme, matrix metalloproteinases, and myeloproteinase, which are released to destroy foreign or self-antigens.
Healthy vs. Infected Wounds: A Clinician's Guide - Net Health nethealth.com Net Health Jun 24, 2025 1 fact
claimBacterial infection increases the production of matrix metalloproteinases (MMPs), which are enzymes that break down the extracellular matrix, leading to the degradation of newly formed collagen and other necessary extracellular matrix components.
Medicinal plants and human health: a comprehensive review of ... link.springer.com Springer Nov 5, 2025 1 fact
claimSecondary metabolites, including catechins, proanthocyanidins, and ellagic acid, inhibit matrix metalloproteinases (MMPs) from degrading the extracellular matrix and invading tumors.
Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Nature Mar 14, 2023 1 fact
claimSenomorphic agents that target matrix metalloproteinases (MMPs) reduce osteoarthritis (OA) symptoms, increase type II collagen, and inhibit chondrocyte degeneration in wild-type (WT) mice.
Unknown source 1 fact
referenceYoung K.A., Hennebold J.D., and Stouffer R.L. published a study in 2002 in Molecular Human Reproduction titled 'Dynamic expression of mRNAs and proteins for matrix metalloproteinases and their tissue inhibitors in the primate corpus luteum during the menstrual cycle'.