concept

MAPK

Also known as: mitogen-activated protein kinase signaling pathway

Facts (5)

Sources

Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us Journal of Food Science & Nutrition 2 facts

claimVitex Negundo perturbs cancer-signaling pathways involving p38, p-ERK1/2, p-JNK, N-Terminal Kinase (JNK), COX-1, MAPK, tumor necrosis factor, vascular endothelial growth factor, and hypoxia-inducible factor in LPS-stimulated cells.

claimSilymarin partially reduces UV-induced apoptosis by activating the Akt, SIRT1, and MAPK pathways, according to Cheon [109].

Medicinal plants and human health: a comprehensive review of ... link.springer.com Springer Nov 5, 2025 2 facts

claimGingerols, derived from Zingiber officinale, demonstrate anti-inflammatory properties by regulating signaling pathways such as MAPK and AP-1.

claimBaicalein from Scutellaria baicalensis and luteolin from other herbs demonstrate anti-neuroinflammatory effects by regulating inflammatory pathways such as NF-κB, MAPK, and JAK-STAT signaling.

Homeostatic medicine: a strategy for exploring health and disease link.springer.com Springer Sep 26, 2022 1 fact

claimNitrate upregulates the expression of cellular signaling pathways including MAPK, PI3K-Akt, mTOR, WNT, glutathione metabolism, and the cell cycle, which are involved in cell regeneration, cell metabolism, and disease progression.