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impaired glucose tolerance
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Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov 11 facts
claimSleep loss, defined as less than 7 hours per night, may have wide-ranging adverse effects on the cardiovascular, endocrine, immune, and nervous systems, including obesity, diabetes, impaired glucose tolerance, cardiovascular disease, hypertension, anxiety symptoms, depressed mood, and alcohol use.
claimThe association between sleep loss and diabetes or impaired glucose tolerance may mediate the relationship between sleep loss and cardiovascular morbidity and mortality.
referenceGottlieb DJ et al. published a study in the Archives of Internal Medicine in 2005 regarding the association between sleep duration and the prevalence of diabetes mellitus and impaired glucose tolerance.
claimAdults with sleep times of 9 hours or more showed increased likelihood of diabetes and impaired glucose tolerance in the Sleep Heart Health Study, a finding consistent with the Nurses Health Study (Gottlieb et al., 2005).
measurementIn the Sleep Heart Health Study, outcomes of impaired glucose tolerance and insulin resistance were more prevalent in individuals with the highest apnea-hypopnea index.
claimAdults with sleep times of 9 hours or more showed increased likelihood of diabetes and impaired glucose tolerance in the Sleep Heart Health Study, a finding consistent with the Nurses Health Study (Gottlieb et al., 2005).
claimObstructive sleep apnea (OSA) is associated with impaired glucose tolerance and insulin resistance, according to data from studies including the Sleep Heart Health Study (Ip et al., 2002; Punjabi et al., 2002; Punjabi et al., 2004).
claimImpaired glucose tolerance is a precursor to diabetes manifested by glucose levels rising higher than normal and for a longer period after an intravenous dose of glucose.
referenceThe Sleep Heart Health Study, a large, cross-sectional, community-based study using polysomnography, found that impaired glucose tolerance and insulin resistance were more prevalent in individuals with the highest apnea-hypopnea index.
claimPotential mechanisms explaining the link between sleep loss and cardiovascular events include blood pressure increases, sympathetic hyperactivity, or impaired glucose tolerance.
measurementAn experimental study by Spiegel et al. (1999) found that restricting 11 healthy male volunteers to 4 hours of sleep for six nights led to impaired glucose tolerance compared to a fully rested state, with glucose clearance being 40 percent slower during sleep loss.
Long-Term Effects of Chronic Sleep Deprivation empowersleep.com Mar 15, 2023 1 fact
referenceA study published in The Lancet found that individuals sleeping less than six hours per night have a higher risk of developing impaired glucose tolerance, which is a precursor to type 2 diabetes.