Knowledge Tree
Immunosenescence
Also known as: human immunosenescence
Facts (10)
Sources
Cellular senescence: from homeostasis to pathological implications ... frontiersin.org 4 facts
referenceImmunosenescence is a factor in aging and successful aging, as discussed by Wang et al. in a 2022 article in Frontiers in Immunology.
referenceThe interplay between immunosenescence and age-related diseases is a subject of study, as reviewed by Barbé-Tuana et al. in a 2020 article in Seminars in Immunopathology.
referenceImmunosenescence acts as a key player in cancer development, according to Lian et al. in a 2020 article in the Journal of Hematology & Oncology.
referenceInflammageing and immunosenescence are interconnected during the aging process, as described by Teissier et al. in a 2022 article in Cells.
A Double-Edged Sword: Inflammation and Your Health - Cedars-Sinai cedars-sinai.org Feb 12, 2021 2 facts
claimImmunosenescence is the process of immune system aging, which causes immune cells to become less responsive and ultimately ineffective.
quoteMaya Koronyo, PhD, stated: "With aging, our bodies undergo a process called immunosenescence, or aging of the immune system. So it's not only your brain and heart that are aging, and your skin that is wrinkling, but there's also a specific process that causes the immune cells to become less responsive and ultimately ineffective."
Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Mar 14, 2023 1 fact
claimPhysical activity may ameliorate immunosenescence and reduce age-related multi-morbidity, as discussed by Duggal et al. in Nature Reviews Immunology (2019).
Chronic inflammation in the etiology of disease across the life span nature.com Dec 5, 2019 1 fact
referencePawelec et al. (2005) explored whether human immunosenescence is infectious in nature.
Homeostatic medicine: a strategy for exploring health and disease link.springer.com Sep 26, 2022 1 fact
referenceFulop T, Larbi A, Dupuis G, Le Page A, Frost EH, Cohen AA, et al. published 'Immunosenescence and Inflamm-aging as two sides of the same coin: friends or foes?' in Frontiers in Immunology in 2017, which discusses the relationship between immunosenescence and inflamm-aging.
Hallmarks and mechanisms of cellular senescence in aging ... - Nature nature.com Aug 4, 2025 1 fact
referenceImmunosenescence involves specific molecular mechanisms and is associated with various diseases, as reviewed by Liu et al. in a 2023 Signal Transduction and Targeted Therapy article.