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human pluripotent stem cells
Also known as: PSCs, human pluripotent stem cell state, human pluripotent stem cell lines
Facts (9)
Sources
Mitochondria and the dynamic control of stem cell homeostasis link.springer.com Apr 16, 2018 8 facts
referenceApáti et al. (2016) reviewed calcium signaling mechanisms in human pluripotent stem cells.
referenceUCP2 regulates energy metabolism and differentiation potential in human pluripotent stem cells, according to Zhang et al. in The EMBO Journal in 2011.
referenceGlycolytic metabolism plays a functional role in regulating the human pluripotent stem cell state, according to Gu et al. (2016).
claimMitochondrial metabolism is important for the self-renewal of human pluripotent stem cells (PSCs), as evidenced by increased activation when lipid levels in the culture media are reduced.
referenceTeSlaa T et al. found in 2016 that α-ketoglutarate accelerates the initial differentiation of primed human pluripotent stem cells.
referenceTohyama S et al. established in 2016 that glutamine oxidation is indispensable for the survival of human pluripotent stem cells.
referenceDistinct metabolic states can support self‐renewal and lipogenesis in human pluripotent stem cells under different culture conditions, according to Zhang et al. in Cell Reports in 2016.
referenceVarum et al. (2011) investigated the differences in energy metabolism between human pluripotent stem cells and their differentiated counterparts.
Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Mar 14, 2023 1 fact
referenceMora et al. (2017) discuss the clinical potentials of human pluripotent stem cells in the journal Cell Biology and Toxicology.