concept

Human Connectome Project

Also known as: HCP

Facts (7)

Sources

A Synergistic Workspace for Human Consciousness Revealed by ... elifesciences.org eLife 7 facts

claimResults from the Human Connectome Project (HCP) dataset indicate that workspace gateways correspond to the brain’s default mode network (DMN) and workspace broadcasters correspond to the executive control network (FPN).

measurementThe study analyzed three resting-state fMRI datasets: 100 subjects from the Human Connectome Project, 15 healthy volunteers scanned before and after propofol-induced general anesthesia, and 22 patients with chronic disorders of consciousness resulting from severe brain injury.

claimThe Human Connectome Project, WU-Minn Consortium, provided data for the research, with Principal Investigators David Van Essen and Kamil Ugurbil and grant number 1U54MH091657.

referenceThe Human Connectome Project datasets are freely available at http://www.humanconnectome.org/.

procedureThe researchers quantified synergistic and redundant interactions between 454 cortical and subcortical brain regions using resting-state functional MRI data from 100 subjects of the Human Connectome Project.

claimThe study's whole-brain results indicate that ΦR disconnections induced by the loss of consciousness function as gateway nodes rather than broadcaster nodes, based on the authors' previous identification of gateways and broadcasters from the Human Connectome Project dataset.

claimThe Human Connectome Project is funded by the 16 NIH Institutes and Centers that support the NIH Blueprint for Neuroscience Research.