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homeostatic overload
Also known as: homeostatic overload thresholds
Facts (11)
Sources
Allostasis revisited: A perception, variation, and risk framework frontiersin.org Sep 28, 2022 11 facts
referenceWhen an animal relies on cues indicating a threat to Potential Reproductive Potential (PRP) and responds with anticipatory elevation in glucocorticoid levels, it can lead to Emergency Life History Stage (ELHS) activation and/or homeostatic overload as described in the Reactive Scope model.
claimHomeostatic overload is most analogous to Type 2 allostatic overload, where prolonged high hormone levels are damaging but an Emergency Life History Stage (ELHS) is not triggered.
referenceHomeostatic overload occurs when high blood levels of a mediator cause damage, specifically exceeding the range of reactive homeostasis.
referenceHomeostatic overload is analogous to the 'level C' regulatory range described in Landys et al. (2006) and is most similar to Type 2 allostatic overload, where prolonged high hormone levels are damaging but an Emergency Life History Stage (ELHS) is not triggered.
referenceWada (2019) suggests that thresholds defined by damage, such as Type II allostatic and homeostatic overload, are difficult to pinpoint because damage accumulation and repair mechanisms are involved.
claimWhen the range of predictive homeostasis is high in a particular life history stage, the extent that hormones may be elevated without inducing homeostatic overload may be smaller.
referenceIn the reactive scope model, acute responses are visualized as spikes in the reactive homeostasis range, and both the frequency and duration of these acute responses are expected to reduce the threshold at which homeostatic overload occurs, as noted by Romero et al. (2009).
claimRomero and Wingfield (2016) noted that homeostatic overload and allostatic overload are related but not identical concepts.
claimType II allostatic and homeostatic overload thresholds are difficult to pinpoint because they involve complex interactions between damage accumulation and repair mechanisms, as noted by Wada (2019).
claimType 1 allostatic overload may lead to homeostatic overload, but this is not always the case; if Emergency Life History Stage (ELHS) activation is short-lived and does not cause damage, it falls within the range of reactive homeostasis.
referenceThe frequency and duration of acute responses are expected to reduce the threshold at which homeostatic overload occurs, according to Romero et al. (2009).