concept

healthy aging

Also known as: successful aging, healthy ageing, healthful aging

Facts (16)

Sources

Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Nature Mar 14, 2023 5 facts

claimNutrient sensing pathways are identified as therapeutic targets for healthy ageing, according to a 2017 review in Expert Opinion on Therapeutic Targets.

referenceMunoz-Carvajal, F. and Sanhueza, M. published a study in 2020 titled 'The mitochondrial unfolded protein response: a hinge between healthy and pathological aging' in Frontiers in Aging Neuroscience, which describes the mitochondrial unfolded protein response as a critical factor distinguishing healthy aging from pathological aging.

referenceMetabolic communication is a key factor in healthy aging, as explored in a 2020 review by Smith et al. in Developmental Cell.

referenceLipids serve as biomarkers of healthy aging according to Almeida, Magalhaes, and Nunes in their 2021 Biogerontology paper.

referenceS. F. Vatner et al. discussed healthful aging mediated by the inhibition of oxidative stress in Ageing Res. Rev. (2020).

Cellular senescence: from homeostasis to pathological implications ... frontiersin.org Frontiers 3 facts

referenceImmunosenescence is a factor in aging and successful aging, as discussed by Wang et al. in a 2022 article in Frontiers in Immunology.

referenceCircadian rhythms and time-restricted feeding are linked to healthy aging, according to Manoogian and Panda (2017).

referenceHommos, M.S., Glassock, R.J., and Rule, A.D. published a study in 2017 in the Journal of the American Society of Nephrology titled 'Structural and functional changes in human kidneys with healthy aging', which details the structural and functional changes that occur in human kidneys during healthy aging.

Chronic inflammation in the etiology of disease across the life span nature.com Nature Dec 5, 2019 2 facts

referenceIntestinal permeability biomarker zonulin is elevated in healthy aging, according to a 2017 study in the Journal of the American Medical Directors Association.

claimInflammation, rather than telomere length, serves as a predictor for successful aging in individuals at extreme old age, according to a 2015 longitudinal study of semi-supercentenarians published in EBioMedicine.

Sleep Across the Lifespan: A Neurobehavioral Perspective link.springer.com Springer Feb 5, 2025 2 facts

claimOne theory suggests that increased napping in older adults compensates for decreased nighttime sleep and is appropriate for normal, healthy aging.

claimSome research posits that older adults have a reduced sleep need, indicated in part by reduced slow wave sleep in healthy aging.

Diet Quality Indices: Measures for Bridging Nutrition and Public Health link.springer.com Springer 2 days ago 1 fact

referenceHu FB (2024) provided an epidemiological perspective on diet strategies for promoting healthy aging and longevity, published in J Intern Med 295(4):508–531.

Short- and long-term health consequences of sleep disruption dovepress.com Goran Medic, Micheline Wille, Michiel EH Hemels · Dove Press May 19, 2017 1 fact

referenceGroeger et al. (2014) published in Sleep that global slow-wave sleep (SWS) disruption and healthy aging have dissociable effects on waking performance and daytime sleepiness.

Associations Between Sleep Duration and Cognitive Function ... humanfactors.jmir.org JMIR Human Factors 1 fact

referenceTian et al. (2024) performed a population-based cohort study examining the association between sleep duration trajectories and successful aging.

Food Consumption Changes in The Ruler Tribal Community bioresscientia.com B. Premagowri · BioRes Scientia Feb 15, 2025 1 fact

claimNutritional behavior, eating patterns, and habits significantly impact human longevity, healthy aging, and disease development.