concept

gonadotropins

Also known as: pituitary gonadotropins, gonadotropin, gonadotrophins

Facts (13)

Sources

The Normal Menstrual Cycle and the Control of Ovulation - NCBI - NIH ncbi.nlm.nih.gov Feingold KR, Adler RA, Ahmed SF · National Center for Biotechnology Information Aug 5, 2018 7 facts

claimDevelopment of the follicle to the preantral stage is gonadotropin-independent, but any follicular growth beyond this point requires gonadotropin interaction.

claimGonadotropin secretion is regulated by gonadotropin-releasing hormone (GnRH), steroid hormones, and various peptides released by the dominant follicle.

referenceReame N. et al. published a study in 1984 in the journal J Clin Endocrinol Metab titled 'Pulsatile gonadotropin secretion during the human menstrual cycle: evidence for altered frequency of gonadotropin-releasing hormone secretion', which analyzes the pulsatile nature of hormone release.

claimGonadotropins are secreted in a pulsatile fashion from the anterior pituitary, with pulse frequency and amplitude varying according to the phase of the menstrual cycle.

referenceFink G. authored a chapter titled 'Gonadotropin secretion and its control' in the 1988 book 'The physiology of reproduction', which covers the regulation of gonadotropin hormones.

referenceYoung J.R. and Jaffe R.B. published a study in 1976 in the journal J Clin Endocrinol Metab titled 'Strength-duration characteristics of estrogen effects on gonadotropin response to gonadotropin-releasing hormone in women. II. Effects of varying concentrations of estradiol', which investigates the hormonal feedback mechanisms in women.

claimGonadotropins are secreted in a pulsatile fashion from the anterior pituitary, with the frequency and amplitude of these pulses varying according to the phase of the menstrual cycle.

Physiology, Male Reproductive System - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov National Library of Medicine 2 facts

claimCastration and chronic steroid treatments affect hypothalamic gonadotropin-releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-alpha knockout mice.

claimBefore puberty, levels of androgens and gonadotropins remain low and constant in males.

Seasonal Changes of Serum Gonadotropins and Testosterone in ... frontiersin.org Frontiers Jan 9, 2020 2 facts

referenceMartikainen et al. (1985) studied circannual concentrations of melatonin, gonadotrophins, prolactin, and gonadal steroids in males living in a geographical area with large annual variations in daylight.

claimGonadotropins, testosterone, and prolactin are the most investigated hormones for detecting the potential persistence of hormone seasonality in humans.

Hormonal changes and sexual function in aging men - PubMed - NIH pubmed.ncbi.nlm.nih.gov PubMed 1 fact

claimTotal and free plasma testosterone levels decline with advancing age in men, while gonadotropin levels increase.

Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu International Academic Publishing House 1 fact

referenceGodam et al. (2021) published 'Xylopia aethiopica ethanol seed extract suppresses Cadmium chloride-induced ovary and gonadotropins toxicity in adult female Wistar rats' in JBRA, demonstrating the protective effects of the extract against cadmium-induced toxicity.