concept

genetic mutation

Also known as: genetic mutations, gene mutations, genetic mutation

Facts (3)

Sources

Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Nature Mar 14, 2023 1 fact

claimA dominant theory in ageing research for decades has been that ageing results from the accumulation of DNA changes, primarily genetic mutations, which cause cells to lose their properties and lead to tissue and organ breakdown.

Homeostatic medicine: a strategy for exploring health and disease link.springer.com Springer Sep 26, 2022 1 fact

claimThe balance between proto-oncogenes and tumor suppressor genes can be disrupted by gene mutations, and the overexpression of proto-oncogenes may lead to abnormal cell proliferation and tumor formation, according to Pitot (1993).

Genetic Targeted Therapy & Precision Oncology mskcc.org Memorial Sloan Kettering Cancer Center 1 fact

claimSeveral newer hormone therapies are specifically indicated for patients with identified gene mutations.