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gene therapy
Also known as: gene therapies
Facts (9)
Sources
Rusty Gage, PhD - Salk Institute salk.edu 5 facts
referenceMaintaining the neuronal phenotype after injury in the adult central nervous system involves neurotrophic factors, axonal growth substrates, and gene therapy, as discussed by Tuszynski and Gage in a 1995 Molecular Neurobiology article.
referenceInder M. Verma and Rusty Gage published 'Genome and gene therapy' in Molecular Therapy in 2000.
referenceF.H. Gage, M.B. Rosenberg, M.H. Tuszynski, K. Yoshida, D.M. Armstrong, R.C. Hayes, and T. Friedmann discussed gene therapy in the central nervous system, specifically the intracerebral grafting of genetically modified cells, in a 1990 Progress in Brain Research publication.
referenceGene therapy for neurologic disease is a field of study reviewed by Fisher, L.J., Schinstine, M., Salvaterra, P., Dekker, A.J., Thal, L., and Gage, F.H. in 1993.
referenceS.T. Suhr and Rusty Gage reviewed the use of recombinant retroviruses for gene therapy in the central nervous system in the 1999 Archives of Neurology.
Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Mar 14, 2023 2 facts
referenceA new intranasal and injectable gene therapy for healthy life extension was reported by Davidsohn et al. in the Proceedings of the National Academy of Sciences (2022).
claimInjected gene therapies for age-related diseases in mice did not alter the animal's native DNA, remained separate from the natural genome, and were not transmitted to subsequent generations.