concept

gene regulatory networks

Also known as: gene regulatory networks, regulatory networks

Facts (11)

Sources

A Hilbertian approach to biological problems | PLOS Complex ... journals.plos.org PLOS Nov 5, 2024 5 facts

claimMethods developed for causal inference from gene perturbation experiments have validated the feasibility of discerning causal structures within gene regulatory networks.

claimBiological robustness in higher organisms is underpinned by an enhanced functional repertoire, which is supported by evolved sophisticated regulatory networks and control mechanisms used to maintain homeostasis and adapt to environmental changes.

claimBiological systems utilize genes to code for sensors, actuators, and regulatory networks that manage them, which provides robustness to variations rather than just basic functionality for survival in ideal circumstances.

claimBiological organisms maintain homeostasis through complex regulatory networks that provide multiple layers of control and feedback mechanisms, allowing them to adapt to changing environments.

claimNetwork motifs are ubiquitous across various biological networks, including metabolic networks and gene regulatory networks, in organisms ranging from plants to worms.

Adaptive laboratory evolution – principles and applications for ... link.springer.com Springer Jul 1, 2013 3 facts

claimGlobal transcription machinery engineering (gTME) can yield results similar to laboratory selection, such as large-scale rewiring of gene regulatory networks.

claimComputational models are well-suited for studying evolutionary change at the population level, but in silico evolution of artificial cells that include simulated regulatory networks is currently very limited.

claimMicrobial gene regulatory networks are generally robust towards perturbations, and large-scale re-wiring of these networks results in a significant number of viable clones with increased evolvability compared to the wildtype.

Medicinal plants and human health: a comprehensive review of ... link.springer.com Springer Nov 5, 2025 2 facts

claimAdvanced sequencing technologies enable scientists to identify key genes responsible for secondary metabolite biosynthesis, understand evolutionary relationships, and discover regulatory networks that control compound production in medicinal plants.

claimMulti-omics integration assists in identifying the regulatory networks that control secondary metabolite production and reveals how plants coordinate multiple biosynthetic pathways.

Feedback Mechanisms | Overview & Research Examples - Perlego perlego.com Perlego 1 fact

claimGene regulatory networks utilize regulatory feedback loops to maintain robustness and influence dynamical properties within the network.