concept

Gene duplication

Also known as: Gene duplication, gene duplications

Facts (12)

Sources

Comparable Ages for the Independent Origins of Electrogenesis in ... journals.plos.org PLOS ONE 7 facts

referenceTaylor JS and Raes J (2004) published 'Duplication and divergence: The evolution of new genes and old ideas' in 'Annu Rev Genet' 38: 615–643.

referenceZhang JZ (2003) published 'Evolution by gene duplication: an update' in 'Trends Ecol Evol' 18: 292–298.

referenceNovak AE, Jost MC, Lu Y, Taylor AD, Zakon HH, et al. (2006) published 'Gene duplications and evolution of vertebrate voltage-gated sodium channels' in 'J Mol Evol' 63: 208–221.

claimGene duplication is considered an important source of raw material for the origin of novel traits, including electrogenesis in teleosts.

referenceOhno S (1970) published 'Evolution by gene duplication', New York: Springer-Verlag, 160 p.

claimArnegard et al. argue that gene duplication can contribute to parallel origins of evolutionary novelty even when gene duplicates are co-opted for innovation long after the initial duplication event.

referenceM.E. Arnegard, D.J. Zwickl, Y. Lu, and H.H. Zakon published 'Old gene duplication facilitates origin and diversification of a new communication system–twice' in the Proceedings of the National Academy of Sciences (PNAS) in 2010, describing how gene duplication events facilitated the evolution of electric communication systems.

Adaptive laboratory evolution – principles and applications for ... link.springer.com Springer Jul 1, 2013 4 facts

referenceKondrashov FA and Kondrashov AS published 'Role of selection in fixation of gene duplications' in the Journal of Theoretical Biology in 2006.

referenceHittinger and Carroll (2007) published 'Gene duplication and the adaptive evolution of a classic genetic switch' in Nature, volume 449, pages 677-681.

referenceInnan H and Kondrashov F published 'The evolution of gene duplications: classifying and distinguishing between models' in Nature Reviews Genetics in 2010.

claimGene duplications are considered a prerequisite for the development of novel molecular functions, though there is ongoing debate regarding whether their long-term fixation is due to selective advantage or random drift.

Medicinal plants and human health: a comprehensive review of ... link.springer.com Springer Nov 5, 2025 1 fact

claimGene duplication events, chromosomal rearrangements, and horizontal gene transfer are the primary drivers in the evolution of plant secondary metabolism.