concept

frontal cortex

Also known as: frontal cortices

Facts (10)

Sources
The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org Frontiers Sep 27, 2017 3 facts
claimAlonso et al. (2015) reported that psychedelics reduce Default Mode Network (DMN) integrity and cause disintegration in normal system functions by reducing connectivity between the frontal cortex and lower brain areas.
claimThe reduction in oscillatory activity and power in the Default Mode Network caused by psilocybin results from decreased functional coupling between the frontal cortex and the medial temporal lobe components of the Default Mode Network, as well as between the medial prefrontal cortex and the posterior cingulate cortex.
claimErnandes proposes that innate operators are based in the R-complex and limbic system, rather than solely in the frontal cortex, as these systems are widely distributed in reptiles and mammals.
Psychedelics, Sociality, and Human Evolution frontiersin.org Frontiers 2 facts
claimThe reinforcement mechanism for psychedelic use in humans is related to intersubjective, social, and symbolic life, and cognitive capacities involving perceptions of greater awareness and profound insights not found in species with less developed frontal cortices.
quoteDavid Nichols (2004) described the cognitive effects of psychedelics as "perceptions of greater awareness, increased understanding, or profound insights that would have no counterpart in lower species with a less developed frontal cortex."
A Synergistic Workspace for Human Consciousness Revealed by ... elifesciences.org eLife 2 facts
claimSome brain connections, particularly in the frontal cortex and lateral prefrontal cortex, exhibited increases in ΦR during loss of consciousness and were restored upon recovery.
claimIn rodents, the administration of carbachol to the frontal cortex awakens rats from sevoflurane anaesthesia.
Consciousness (Stanford Encyclopedia of Philosophy/Fall 2025 ... plato.stanford.edu Stanford Encyclopedia of Philosophy Jun 18, 2004 1 fact
perspectiveSupporters of the global neuronal workspace model, such as Stanislas Dehaene (2000), argue that consciousness requires contents to be activated with a large-scale pattern of recurrent activity involving frontal, parietal, and primary sensory areas of the cortex.
Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov Colten HR, Altevogt BM · National Academies Press 1 fact
measurementWhen transitioning from waking to non-REM (NREM) sleep, depressed subjects show smaller decreases in relative metabolism in regions of the frontal, parietal, and temporal cortex compared to healthy individuals, according to Nofzinger et al. (2005) using positron emission tomography.
The function(s) of consciousness: an evolutionary perspective frontiersin.org Frontiers in Psychology Nov 25, 2024 1 fact
referenceBadre and Nee (2018) published 'Frontal cortex and the hierarchical control of behavior' in Trends in Cognitive Sciences.