Knowledge Tree
Eugenol
Facts (22)
Sources
Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us 12 facts
claimEugenol, ursolic acid, linalool, and isoeugenol exhibit anti-neoplastic and anticancer properties by restricting cancer cell growth through apoptosis induction, cellular blockade, and inhibition of DNA synthesis, specifically demonstrating cytotoxic activity against Michigan Cancer Foundation-7 cells.
claimEugenol, linalool, estragole, 1,8-cineole, and α-terpineol in Ocimum basilicum Linn. exhibit anti-bacterial activity by degrading bacterial cell walls, damaging cytoplasmic membrane proteins, binding proteins, causing leakage of cell contents, coagulating cytoplasm, and depleting the proton motive force, according to Opalchenova et al. and Adiguzel et al.
claimEugenol, linalool, and rosmarinic acid provide cardioprotective and hepatoprotective benefits by preventing hyperlipidemia, protecting hepatic tissue from oxidant damage, and preventing hepatic fibrosis.
measurementEugenol found in Ocimum basilicum Linn. has the chemical formula C10H12O2, a molecular weight of 164.2, and the identifier 3314.
claimEstragole, linalool, eugenol, and methyl cinnamate in Ocimum basilicum Linn. exhibit anti-fungal activity by reducing DNA binding formation of aflatoxins, reacting with reactive oxygen species (ROS) increased by aflatoxins, and inhibiting mycelium growth, spore germination, and germ tube elongation, according to Gucwa et al. and Nugroho et al.
claimEugenol, apigenin, linalool, and ursolic acid in Ocimum basilicum Linn. exhibit antiviral activity by preventing viral attachment and entry into host cells, and by inhibiting hepatitis B virus production through interference with viral infection and replication, according to Chiang et al. and Chattopadhyay et al.
claimEugenol, linalool, methyl eugenol, anthocyanins, and 1,8-cineole exhibit anti-ulcer activity by decreasing pepsin and acid production, and providing lipoxygenase inhibitory, histamine antagonistic, and antisecretory effects.
claimLinalool and eugenol found in Ocimum basilicum Linn. exhibit analgesic activity by inducing inhibition of cyclo-oxygenase activity and inhibiting pain mediator biosynthesis, including prostaglandins, prostacyclin, and opioid receptor interactions, according to Govindarajan et al.
claimRosmarinic acid, estragole, linalool, eugenol, methyl cinnamate, linoleic acid, α-cadinol, and α-bergamotene exhibit antioxidant activity by scavenging free radicals and protecting against oxidative stress through the increase of antioxidative defense enzymes.
claimEugenol, linalool, and estragole in Ocimum basilicum Linn. show broad-spectrum antimicrobial activity against various pathogenic strains of bacteria, viruses, fungi, and parasites, according to Sakkas et al.
claimEstragole, methyl cinnamate, methyl eugenol, α-bergamotene, α-cadlnol, linalool, eugenol, and linoleic acid in Ocimum basilicum Linn. exhibit anti-inflammatory activity by inhibiting pro-inflammatory mediators, stimulating anti-inflammatory cytokines, decreasing nitric oxide production, and inhibiting lipoxygenase and cyclooxygenase enzymes, according to Mueller et al., Umamageswari et al., and Eftekhar et al.
claimApigenin, linalool, and eugenol possess anti-osteoporotic effects by inducing apoptosis in mature osteoclasts, inhibiting bone resorption, and inducing osteoblastic differentiation.
Medicinal plants: bioactive compounds, biological activities ... frontiersin.org 10 facts
referenceVachhani et al. (2022) conducted a comparative clinical and radiographic evaluation of zinc oxide–Ocimum sanctum extract, zinc oxide–ozonated oil, and zinc oxide–eugenol as obturating materials in primary molars, published in the Journal of the Indian Society of Pedodontics and Preventive Dentistry.
claimEugenol is a phyto-compound effective against methicillin-resistant and methicillin-sensitive Staphylococcus aureus clinical strain biofilms.
claimEugenol efficiently eradicates Staphylococcus aureus biofilms in vivo, diminishes the expression of genes linked to biofilms and enterotoxins, disrupts the cell membrane, and results in the release of cellular contents.
claimEugenol demonstrates antifungal capabilities and the capacity to inhibit oral microorganisms associated with periodontal disease and dental caries.
referenceMarchese et al. (2017) reviewed the antimicrobial activity and mechanistic viewpoint of eugenol and essential oils containing eugenol in the journal Critical Reviews in Microbiology.
claimEugenol, a bioactive compound found in Syzygium aromaticum (clove), is effective against the MDR microorganisms Staphylococcus aureus and Candida albicans.
claimEugenol derived from Syzygium aromaticum (clove) exhibits antibacterial properties against Staphylococcus aureus ATCC 29213 and MRSA clinical isolates, and it impedes biofilm production.
claimThe medicinal benefits of the plants used in the “Baker” herbal steam bath are linked to volatile oil constituents, specifically eugenol, β-pinene, sabinene, and zingiberene.
claimTerpenes possess lipophilic characteristics that allow them to infiltrate bacterial cell membranes, resulting in damage and demonstrating antibacterial or bactericidal properties, as evidenced by carvacrol, thymol, and eugenol against several bacterial strains.
claimEugenol is utilized as a counterirritant, topical antiseptic, and in dentistry, where it is frequently coupled with zinc oxide for analgesia and root canal obturation.