concept

Epidermal Growth Factor Receptor

Also known as: EGFR, ERBB1

Facts (4)

Sources

Cellular senescence: from homeostasis to pathological implications ... frontiersin.org Frontiers 1 fact

claimEGFR oncogenic mutations in non-small cell lung cancer (NSCLC) impair macrophage phagocytosis and mediate innate immune evasion by up-regulating CD47.

What is Targeted Therapy? Know Before Treatment | UT MD Anderson mdanderson.org MD Anderson Cancer Center 1 fact

claimEGFR stands for epidermal growth factor receptor, which is a protein found on the surface of some tumor cells and also in the epidermis, the top layer of skin.

Medicinal plants and human health: a comprehensive review of ... link.springer.com Springer Nov 5, 2025 1 fact

referenceBaicalein inhibits the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) by directly binding to the Epidermal Growth Factor Receptor (EGFR) and enhancing the immune response, according to a 2025 study by Wu et al.

Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Nature Mar 14, 2023 1 fact

claimDeep proteomic analysis of large-scale populations confirms that plasma proteins sclerostin, pleiotrophin, and transgelin increase with aging, while epidermal growth factor receptor (ERBB1) and α2-antiplasmin decrease with age.