Knowledge Tree
drugs of abuse
Facts (7)
Sources
From crayfish to humans: An evolutionary perspective of addiction redalyc.org 6 facts
claimRepeated contact with drugs of abuse causes a disconnection with prefrontal structures that are responsible for curbing harmful behavior, according to Goldstein and Volkow (2011).
claimDrugs of abuse activate the brain's reward system and promote a misleading signal that announces the arrival of a significant benefit for survival, according to Nesse and Berridge (1997).
claimThe evolutionary perspective suggests that the effects of psychoactive substances and drugs of abuse on the brain are a side effect of evolution.
claimDrugs of abuse increase the release of neurotransmitters, primarily dopamine, in the brain's reward circuitry.
claimAddicted individuals often become less responsive to natural reinforcers because those reinforcers lose value compared to the reinforcing signal provided by drugs of abuse.
claimDrugs of abuse modulate behavior by acting on the brain reward system.
Effects of psychedelics on neurogenesis and broader neuroplasticity link.springer.com Dec 19, 2024 1 fact
referenceA. Papaseit et al. reviewed the interactions of MDMA with pharmaceuticals and drugs of abuse in a 2020 article published in Expert Opinion on Drug Metabolism & Toxicology.