Knowledge Tree
drug resistance
Facts (10)
Sources
Medicinal plants: bioactive compounds, biological activities ... frontiersin.org 4 facts
claimDrug resistance in pathogenic microorganisms can be intrinsic or acquired, with foreign-resistant genes introduced into recipient organisms through transformation, transduction, or conjugation.
referenceVasan, Baselga, and Hyman published 'A view on drug resistance in cancer' in the journal Nature in 2019.
claimEscherichia coli and Staphylococcus aureus pose a significant challenge in underdeveloped countries due to their ability to acquire drug resistance.
claimExcessive use of antibiotics increases the drug resistance of Staphylococcus aureus.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu 2 facts
referenceAyaz et al. (2019) propose that the synergistic interaction of phytochemicals with antimicrobial agents is a potential strategy to counteract drug resistance.
referenceGanapathi and Ganapathi (2013) published 'Mechanisms regulating resistance to inhibitors of topoisomerase II' in Frontiers in Pharmacology, detailing the mechanisms behind drug resistance to these specific inhibitors.
Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 1 fact
claimPhytochemicals offer advantages over traditional chemotherapeutic drugs, including lower systemic toxicity, multi-target efficacy, and the ability to overcome drug resistance mechanisms.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... ouci.dntb.gov.ua 1 fact
referenceM. Ayaz, F. Ullah, A. Sadiq, F. Ullah, M. Ovais, J. Ahmed, and H. P. Devkota examined the synergistic interactions of phytochemicals with antimicrobial agents as a strategy to counteract drug resistance in a 2019 article published in Chemico-Biological Interactions.
Medicinal plants: bioactive compounds, biological activities ... pubmed.ncbi.nlm.nih.gov Apr 28, 2025 1 fact
claimThe rapid spread of multidrug-resistant infections is primarily attributed to improper prescriptions, overuse, and unregulated access to antibiotics.
Homeostatic medicine: a strategy for exploring health and disease link.springer.com Sep 26, 2022 1 fact
claimInorganic nitrate does not exhibit the same drug resistance as organic nitrate, as evidenced by a significant antihypertensive effect observed after one year of use (Munzel et al. 2005).