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dopamine agonists
Also known as: dopaminergic agonists, dopaminergic agonist drugs
Facts (11)
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Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov 11 facts
claimDopamine agonists are associated with sleep attacks and daytime sleepiness in patients with Parkinson’s disease, as reported in a 2003 study in Movement Disorders.
referenceCantor CR and Stern MB reviewed the effects of dopamine agonists on sleep in patients with Parkinson’s disease, published in Neurology in 2002.
claimExcessive daytime sleepiness, including sleep attacks, has been associated with the use of dopamine agonists in Parkinson’s disease patients (Paus et al., 2003).
claimParkinson’s disease is commonly treated with dopamine precursors (levodopa/carbidopa) and dopamine agonists (pramipexole and ropinirole).
claimDopamine antagonists usually worsen Restless Legs Syndrome symptoms, while dopaminergic agonists are used to treat the condition.
claimExcessive daytime sleepiness, including sleep attacks, has been associated with the use of dopamine agonists in patients with Parkinson’s disease, often requiring the use of daytime stimulants such as modafinil or amphetamine to relieve the sleepiness.
claimThe ability to ameliorate REM sleep behavioral disorder symptoms with dopaminergic agonist drugs suggests that the disorder may be an early sign of damage to the dopaminergic system (Trampus et al., 1991).
claimParkinson’s disease is commonly treated with dopamine precursors such as levodopa/carbidopa and dopamine agonists such as pramipexole and ropinirole.
claimLow doses of dopamine precursors and dopamine agonists can promote sleep, but high doses may cause increased nocturnal wakefulness, decreased slow-wave sleep (SWS), and decreased sleep continuity (Leeman et al., 1987; Monti et al., 1988; Cantor and Stern, 2002).
claimMedications used to treat Parkinson’s disease, specifically dopamine precursors like levodopa/carbidopa and dopamine agonists like pramipexole and ropinirole, can promote sleep when used in low doses, but high doses may cause increased nocturnal wakefulness, decreased slow-wave sleep (SWS), and decreased sleep continuity (Leeman et al., 1987; Monti et al., 1988; Cantor and Stern, 2002).
claimEffective pharmacological treatments for REM sleep behavior disorder include long-acting benzodiazepines, clonazepam, and dopamine agonists.