concept

DNA repair

Also known as: DNA repair, DNA damage repair

Facts (9)

Sources

Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Nature Mar 14, 2023 3 facts

claimNicotinamide mononucleotide (NMN) protects skin cells, such as keratinocytes, from UV radiation-caused DNA damage by enhancing DNA repair, which contributes to reversing skin ageing.

claimNAD+ acts as a hydride-accepting coenzyme involved in DNA repair and the preservation of genome stability, and increased levels of NAD+ reduce DNA damage.

referenceWatanabe et al. (2017) proposed that nucleosome remodeling, DNA repair, and transcriptional regulation collectively establish negative feedback loops involved in cancer development and cellular aging.

Extremophiles: Unlocking biomedical and industrial innovations ... cas.org CAS Oct 29, 2025 2 facts

claimRadiation-resistant bacteria with unprecedented DNA repair capabilities have been isolated from nuclear waste sites.

claimThe fungus Cladosporium chernobylensis, found in the Chernobyl Exclusion Zone, utilizes DNA repair and melanin production as survival strategies.

Life on the Edge: Bioprospecting Extremophiles for Astrobiology link.springer.com Springer May 19, 2023 1 fact

claimIt is speculated that the stress resistance observed in organisms like Deinococcus radiodurans is primarily associated with efficient DNA repair and antioxidant systems that protect cellular components from oxidative damage.

Short- and long-term health consequences of sleep disruption dovepress.com Goran Medic, Micheline Wille, Michiel EH Hemels · Dove Press May 19, 2017 1 fact

claimMelatonin possesses properties including DNA repair, inhibition of tumor growth, and acting as a potent free-radical scavenger.

Medicinal plants: bioactive compounds, biological activities ... frontiersin.org Frontiers in Immunology 1 fact

claimSpontaneous mutations, which cause antimicrobial resistance, occur in actively dividing cells as random replication mistakes or improper DNA damage repair.

Adaptive laboratory evolution – principles and applications for ... link.springer.com Springer Jul 1, 2013 1 fact

procedureLaboratory evolution experiments can accelerate the selection process by increasing the diversity of targets for selection through the application of chemical mutagens, mutants deficient in DNA repair, or transposon libraries.