Knowledge Tree
cytotoxicity
Also known as: cytotoxic activity, cytotoxic effects
Facts (15)
Sources
Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us 6 facts
claimSilymarin enriched extract from Silybum marianum has an additive effect on Doxorubicin-mediated cytotoxicity in PC-3 prostate cancer cells, according to a 2019 study by Gioti K et al.
claimAllyl retrochalcone isolated from the roots of Glycyrrhiza exhibits cytotoxic activity.
claimGlycocoumarin, licopyranocoumarin, and licochalcone A inhibit the growth of giant cell structures in HIV-infected cell cultures without cytotoxic activity, according to De Simone et al. (reference 84).
claimTorres et al. (2018) found that Ocimum basilicum, but not Ocimum gratissimum, presents cytotoxic effects on the human breast cancer cell line MCF-7, inducing apoptosis and triggering the mTOR/Akt/p70S6K pathway.
claimSilymarin induces cytotoxicity in prostate cancer cells, according to Gioti et al. [98].
claimLicochalcone E, isolated from Glycyrrhiza inflata root extract, shows potent cytotoxic activity in comparison with standard antineoplastic drugs, according to Yoon et al. (reference 82).
Medicinal plants: bioactive compounds, biological activities ... frontiersin.org 3 facts
referenceArullappan S, Rajamanickam P, Thevar N, and Kodimani CC published a 2014 study in the Tropical Journal of Pharmaceutical Research titled 'In vitro screening of cytotoxic, antimicrobial and antioxidant activities of Clinacanthus nutans (Acanthaceae) leaf extracts', which assesses the biological activities of this plant.
referenceGhuman S, Ncube B, Finnie J, McGaw LJ, Coopoosamy RM, and Van Staden J published a 2016 study in Frontiers in Pharmacology titled 'Antimicrobial activity, phenolic content, and cytotoxicity of medicinal plant extracts used for treating dermatological diseases and wound healing in KwaZulu-Natal, South Africa', which examines the medicinal properties of local plants.
claimAdministering high doses of antibiotics to treat localized infections can lead to cytotoxicity and adverse reactions in surrounding tissues, potentially hindering patient recovery.
Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 1 fact
referenceNikolova et al. (2023) published an update on biogenic metallic and metal oxide nanoparticles, focusing on their applications in therapy, drug delivery, and their cytotoxicity profiles.
Phytobioactive compounds as therapeutic agents for human ... onlinelibrary.wiley.com Apr 17, 2023 1 fact
claimPolyphenols, alkaloids, terpenes, and polysaccharides isolated from medicinal plants exhibit antioxidant, anticancer, cytotoxic, and anti-inflammatory biological activities.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... ouci.dntb.gov.ua 1 fact
referenceTiwary et al. (2015) evaluated the in vitro cytotoxic activity of ethno-pharmacologically important plants from the Darjeeling district of West Bengal against human cancer cell lines, published in BMC Complementary and Alternative Medicine.
Recent breakthroughs in the valorization of lignocellulosic biomass ... pubs.rsc.org Jun 7, 2025 1 fact
measurementThe CNC-doped bio-furan elastomer developed by Koo et al. exhibits a tensile strength of 67 MPa, which is 7 times greater than synthetic thermoplastic urethanes, an extensibility of 8.6 folds, and negligible in vivo cytotoxicity.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu 1 fact
referenceEthno-pharmacologically important plants from the Darjeeling district of West Bengal exhibit in vitro cytotoxic activity against various human cancer cell lines.
Medicinal Plants and their Traditional Uses - Open Access Pub openaccesspub.org 1 fact
referenceKuete V, Seo E J, Krusche B, Oswald M, and Wiench B published 'Cytotoxicity and pharmacogenomics of medicinal plants from traditional Korean medicine' in Evidence-Based Complementary and Alternative Medicine in 2013.