concept

CRISPR-Cas9

Also known as: CRISPR-Cas9, CRISPR/Cas, CRISPR, clustered regularly interspaced short palindromic repeats

Facts (9)

Sources

Engineering biology applications for environmental solutions - Nature nature.com Nature Apr 14, 2025 2 facts

claimThe increasing application of CRISPR-Cas and Directed Accelerated Revision Technology to a broader range of microbes creates new opportunities and challenges for environmental synthetic biology biosafety and biosecurity.

claimThere is no fundamental distinction between a markerless engineered organism modified via CRISPR and one modified using selectable markers like sacB.

Extremophiles: Unlocking biomedical and industrial innovations ... cas.org CAS Oct 29, 2025 2 facts

claimDeinococcus radiodurans provides DNA-repair templates that can enhance CRISPR accuracy and reduce off-target effects.

claimResearchers utilize computational modeling and CRISPR-based pathway engineering to address challenges in compound scalability and structure-activity optimization for extremophile bioactive discovery.

Read "Review and Assessment of Planetary Protection Policy ... nap.nationalacademies.org National Academies of Sciences, Engineering, and Medicine 2 facts

claimThe biological research community, having previously addressed ethical issues in research such as CRISPR, is well-positioned to address similar ethical issues within the context of space exploration.

claimCRISPR (clustered regularly interspaced short palindromic repeats) is a genome editing technique that uses a specific sequence of DNA and its associated protein to add or remove specific gene sequences to a cell.

The role of extremophile microbiomes in terraforming Mars - Nature nature.com Nature Nov 17, 2025 1 fact

claimGenome editing technologies like CRISPR-Cas, synthetic regulatory circuits, and modular design principles allow for the reprogramming of microbial life to survive and function under Martian conditions.

Medicinal plants and human health: a comprehensive review of ... link.springer.com Springer Nov 5, 2025 1 fact

referenceAlariqi et al. (2025) published a study in Advanced Science regarding methods to enhance the specificity, precision, accessibility, flexibility, and safety of CRISPR/Cas editing to overcome traditional challenges.

Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Nature Mar 14, 2023 1 fact

claimResearchers identified the histone acetyltransferase gene KAT7 as a driver of senescence in Werner syndrome (WS) and Hutchinson-Gilford progeria syndrome (HGPS) models using genome-wide CRISPR-Cas9-based screening.