concept

corticosterone

Also known as: corticosterone levels

Facts (10)

Sources

Allostasis revisited: A perception, variation, and risk framework frontiersin.org Frontiers Sep 28, 2022 6 facts

claimThe enzyme 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) protects mineralocorticoid receptor-expressing tissues from glucocorticoid activation by breaking down corticosterone and cortisol.

claimJimeno, Hau, and Verhulst (2018) found that corticosterone levels reflect variation in metabolic rate, independent of stress.

referenceCrino, Driscoll, and Breuner (2014) found that corticosterone exposure during development has sustained, but not lifelong, effects on body size and corticosterone responses in the zebra finch.

claimLattin et al. (2011) validated that elevated corticosterone in feathers correlates with corticosterone-induced decreased feather quality.

referenceModern elasmobranchs possess both glucocorticoid and mineralocorticoid receptor types, utilize corticosterone and 1α-hydroxycorticosterone as potential agonists, and express 11β-hydroxysteroid dehydrogenase (HSD) type 2 enzymes, as noted by Carroll et al. (2008) and Baker et al. (2013).

referenceVera et al. (2017) discussed expanding the actions of cortisol and corticosterone in wild vertebrates as a necessary step to overcome emerging challenges, published in General and Comparative Endocrinology.

The lunar cycle: effects on human and animal behavior and physiology pubmed.ncbi.nlm.nih.gov PubMed 1 fact

claimIn birds, daily variations in melatonin and corticosterone disappear during full-moon days.

Wild edible plants for food security, dietary diversity, and nutraceuticals frontiersin.org Frontiers Nov 27, 2025 1 fact

referenceDioscorea deltoidea (yam) is used to eliminate intestinal worms and parasites, treat urogenital disorders, and reduce joint pain, with immunomodulatory and anthelmintic bioactivity, containing diosgenin, corticosterone, and deltostim, as reported by Semwal et al. (2021).

Integrating allostasis and emerging technologies to study complex ... nature.com Nature Nov 5, 2025 1 fact

claimChronic unpredictable stress elevates serum corticosterone and serum IL-6 levels, while simultaneously causing microglia activation and a decrease in TGF-β.

Effects of psychedelics on neurogenesis and broader neuroplasticity link.springer.com Springer Dec 19, 2024 1 fact

accountWankhar et al. (2020) demonstrated that 1-Methylpsilocin treatment alleviated behavioral signs of anxiety and anhedonic phenotype by the seventh day post-CUS, rescued subjects from CUS-induced mitochondrial damage, balanced 5-HT/5-HT2CR levels in the PFC and hippocampus, and mitigated hippocampal cell morphological abnormalities and elevated corticosterone levels.