Knowledge Tree
claustrum
Facts (21)
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The evolution of human-type consciousness – a by-product of ... frontiersin.org 12 facts
referenceNikolenko et al. (2021) published 'The mystery of claustral neural circuits and recent updates on its role in neurodegenerative pathology' in Behavioural Brain Research, detailing the function of the claustrum.
claimThe author identifies the claustrum as the leading candidate for the anatomical location of the interface between chaotic and linear brain activity.
claimThe claustrum is hypothesized to be a location for consciousness (Crick and Koch, 2005) and is also hypothesized to be a source of innovation.
referenceThe claustrum has been described in scientific literature as "intriguing" (Atlan et al., 2018), "enigmatic" (Torgerson and Van Horn, 2014), and having a functional role that "remains unknown" (Atilgan et al., 2022) or is "least understood" (Nikolenko et al., 2021).
claimThe claustrum consists mainly of one type of nerve cell, making it less complex than most other brain structures despite its extensive connectivity.
claimMany mammals possess similar innovation systems with similar interfaces because they share neural structures such as the neocortex, the claustrum (excluding monotremes), and the default mode network.
referenceAtilgan et al. (2022) published 'Human lesions and animal studies link the claustrum to perception, salience, sleep and pain' in Brain, volume 145, pages 1610–1623.
claimThe claustrum is the brain structure most connected to the rest of the brain relative to its volume, with links to most parts of the neocortex, including the default network.
referenceCrick and Koch (2005) investigate the function of the claustrum in the brain.
referenceFrancis Crick and Christof Koch (2005) were the first to associate the claustrum with consciousness and proposed that the neocortex is represented within the claustrum in a partial and "diluted" manner.
referenceThe article 'The evolution of human-type consciousness – a by-product of mammalian innovation mechanism – a preliminary hypothesis' cites Torgerson and Van Horn (2014), which provides a case study on the history, mapping, and connectivity of the claustrum.
claimThe claustrum is hypothesized as a potential anatomical location for the interface of conscious experience, though current scientific understanding of its specific modes of action remains speculative.
Psychedelics and Consciousness: Distinctions, Demarcations, and ... ouci.dntb.gov.ua 5 facts
referenceAtlan published 'The claustrum supports resilience to distraction' in Current Biology, No. 28, p. 2752.
referenceMathur provided a review of the claustrum in Frontiers in Systems Neuroscience (Volume 8, page 48).
referenceFrancis Crick investigated the function of the claustrum in a paper published in Philosophical Transactions of the Royal Society B: Biological Sciences (2005).
referenceWhite et al. published 'Anterior cingulate cortex input to the claustrum is required for top-down action control' in Cell Reports, which identifies the role of the anterior cingulate cortex and claustrum in action control.
referenceKrimmel studied resting state functional connectivity and cognitive task-related activation of the human claustrum, published in Neuroimage (Volume 196, page 59).
Published Studies — Johns Hopkins Center for Psychedelic and ... hopkinspsychedelic.org 2 facts
claimPsilocybin acutely alters the functional connectivity of the claustrum with brain networks that support perception, memory, and attention.
referenceLevin, A., Nagib, P. B., Deiparine, S., Gao, T., Mitchell, J., & Davis, A. K. published a study titled 'A role for the claustrum in cognitive control' in the journal Trends in Cognitive Sciences in 2022.
Ancient Roots of Today's Emerging Renaissance in ... link.springer.com 2 facts
claimClassic psychedelics initiate a cascade of altered neural connectivity and blood-flow across brain regions including the default-mode network (medial prefrontal cortex, posterior cingulate cortex, inferior parietal lobule, lateral temporal cortex, hippocampus, and precuneus), the amygdala, the thalamus, and the claustrum.
referenceFrederick Barrett, Samuel Krimmel, Roland Griffiths, David Seminowicz, and Brian Mathur found that psilocybin acutely alters the functional connectivity of the claustrum with brain networks involved in perception, memory, and attention.