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Candida albicans
Also known as: C. albicans
Facts (28)
Sources
Medicinal plants: bioactive compounds, biological activities ... frontiersin.org 24 facts
claimCandida albicans is responsible for the heightened prevalence of vulvovaginal candidiasis in women of reproductive age, particularly those who are HIV-positive.
measurementCandida albicans yeast cells are spherical to oval, measuring 3 to 5 µm in width and 5 to 10 µm in length.
claimCandida albicans is the etiology of vulvovaginal and oropharyngeal candidiasis.
claimCandida albicans virulence factors bind to endothelial cells in blood vessels and epithelial cells in the respiratory tract, influencing pseudo-hyphae development.
claimHoney flavonoids and quercetin impede the growth of Candida albicans by increasing intracellular reactive oxygen species levels.
claimCandida albicans is the sixth most prevalent pathogen in the bloodstream for both acute and chronic yeast infections in humans and is a recognized source of nosocomial infections, particularly in immunocompromised individuals.
claimThe initial report of Candida albicans strains exhibiting resistance to azole antifungals occurred in the late 1980s.
claimInvasive nosocomial infections caused by Candida albicans can present as urinary tract infections, surgical site infections, bloodstream infections (fungemia), catheter-associated skin abscesses, and myocarditis.
measurementThe leaf extract of Clinacanthus nutans demonstrated antifungal activity against Candida albicans in a laboratory environment with a minimum inhibitory concentration (MIC) above 1 mg/mL.
claimTomatidine, a bioactive compound found in Solanum tuberosum (potato), is effective against the MDR microorganism Candida albicans.
claimSantra et al. demonstrated that plumbagin, derived from the plant Plumbago zeylanica, produces oxidative stress in Candida albicans, leading to fungal cell death.
claimThe invasive hyphae of Candida albicans allow the organism to disseminate throughout affected tissue or organ, whereas yeast cells disseminate to many regions.
claimSurface recognition molecules, hyphal switching, and phenotypic switching facilitate the binding of Candida albicans to host cells.
claimPyrus salicifolia (willow-leaved pear), originating from Asia, demonstrated in vitro antimicrobial activities against Bacillus subtilis, Bacillus pumalis, Candida albicans, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus.
claimThe prenyflavanone 8PP inhibits Candida albicans biofilms by enhancing the generation of reactive oxygen and nitrogen species.
claimArtemisia dracunculus (tarragon), originating from Eurasia, demonstrated in vitro antimicrobial activities against Candida albicans, Xanthomonas maltophilia, and Proteus mirabilis.
referenceLiu et al. (2023) published a study in ACS Infectious Diseases on the biosensor-enabled discovery of CaERG6 inhibitors and their antifungal mode of action against Candida albicans.
claimExtracellular hydrolytic enzymes facilitate the adhesion, tissue infiltration, invasion, and destruction of host tissue by Candida albicans.
claimEugenol, a bioactive compound found in Syzygium aromaticum (clove), is effective against the MDR microorganisms Staphylococcus aureus and Candida albicans.
claimCandida albicans, Enterococcus faecalis, E. coli, P. aeruginosa, and S. aureus are identified as the most common bacteria and yeast responsible for microbial infections in underdeveloped nations.
claimHemolysin is a virulence factor in Candida albicans that facilitates sickness by inducing erythrocyte lysis, which enhances iron absorption necessary for yeast growth and pathogenic functions.
claimAnethum graveolens (dill), originating from the Mediterranean, Europe, and Asia, demonstrated in vitro antimicrobial activity against Candida albicans and Staphylococcus aureus.
claimCandida albicans can alternate between two unique forms: a unicellular yeast that reproduces via budding and a form that produces elongated filaments comprising pseudomycelium.
claimDioscorea bulbifera (air potato), originating from Tropical Africa and Asia, demonstrated in vitro antimicrobial activities against Bacillus subtilis, Bacillus pumalis, Candida albicans, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus.
Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us 2 facts
claimSilibinin triggers yeast apoptosis in Candida albicans by causing a mitochondrial calcium influx, according to a 2016 study by Yun DG and Lee DG.
claimSilymarin destabilizes mature biofilms, inhibits the secretion of hydrolases, and mediates the destruction of the membrane in Candida albicans, according to Yun et al. (reference 88).
Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 1 fact
measurementEpigallocatechin gallate (EGCG) derived from Camellia sinensis demonstrates antifungal efficacy against Candida albicans with a minimum inhibitory concentration (MIC) of 16 μg/mL, reducing ergosterol levels by 80% within 24 hours of administration.
Medicinal plants meet modern biodiversity science - OUCI ouci.dntb.gov.ua 1 fact
measurementThe aqueous extract of in vitro grown snow mountain garlic bulbils (TC-SMG) demonstrated antifungal activity against Candida species, with a zone of inhibition of 22.30±0.33 mm against C. albicans, 17.3±0.33 mm against C. tropicalis, and 19.3±0.33 mm against C. glabrata using a 200 mg/mL extract concentration after 24 hours.