Knowledge Tree
cancer development
Facts (8)
Sources
Integrating allostasis and emerging technologies to study complex ... nature.com Nov 5, 2025 3 facts
claimPersistent allostatic states driven by chronic stressors are linked to cancer development.
perspectiveThe utility of the allostatic load index in predicting cancer development and prognosis is controversial, with findings varying across populations, cancer types, and assessment methods.
claimDai, S. et al. (2020) asserted that chronic stress promotes cancer development, as published in Frontiers in Oncology.
Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Mar 14, 2023 2 facts
referenceWatanabe et al. (2017) proposed that nucleosome remodeling, DNA repair, and transcriptional regulation collectively establish negative feedback loops involved in cancer development and cellular aging.
referencePremature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation, according to Pennarossa et al. in Cell (2014).
How Therapeutics Discovery is developing targeted therapies for ... mdanderson.org Jan 19, 2021 1 fact
claimDisruptions to the epigenome are a hallmark of cancer development, making epigenetic functions an attractive target for cancer therapies.
Cellular senescence: from homeostasis to pathological implications ... frontiersin.org 1 fact
referenceImmunosenescence acts as a key player in cancer development, according to Lian et al. in a 2020 article in the Journal of Hematology & Oncology.
Mitochondria and the dynamic control of stem cell homeostasis link.springer.com Apr 16, 2018 1 fact
referenceMitochondria play a role in cancer development, as discussed by Zong et al. in Molecular Cell in 2016.