Knowledge Tree
Bacillus subtilis
Also known as: Bacillus subtilis AH18
Facts (12)
Sources
Life on the Edge: Bioprospecting Extremophiles for Astrobiology link.springer.com May 19, 2023 5 facts
referenceMoeller R et al. reported in 2014 that the resistance of Bacillus subtilis spore DNA to lethal ionizing radiation relies primarily on spore core components and DNA repair mechanisms, with oxygen radical detoxification playing a minor role.
referenceChung S, Lim HM, and Kim SD developed a formulation of Bacillus subtilis AH18 in 2007 that is stable against temperature fluctuations, utilizing highly heat-resistant endospores and micropore inorganic carriers.
referenceFajardo-Cavazos P et al. demonstrated in 2005 that Bacillus subtilis spores can survive hypervelocity atmospheric entry when placed on artificial meteorites, which has implications for the theory of lithopanspermia.
referenceBacillus subtilis spores demonstrate resistance to simulated Mars surface conditions, as reported by Cortesão et al. (2019).
referenceNuding et al. (2017) investigated the survival of Bacillus subtilis spores in deliquescent salt marsh analog environments, published in Astrobiology 17(10):997–1008.
The role of extremophile microbiomes in terraforming Mars - Nature nature.com Nov 17, 2025 3 facts
claimEngineered auxotrophy, UV-inducible toxin-antitoxin circuits, and substrate-dependent growth modules in Bacillus subtilis are proposed as biocontainment strategies for extraterrestrial deployment.
referenceGodin, P. J., Schuerger, A. C. & Moores, J. E. published 'Salt Tolerance and UV Protection of Bacillus subtilis and Enterococcus faecalis under Simulated Martian Conditions' in Astrobiology in 2021.
claimBacillus subtilis spores exhibit resilience by surviving acidic, Fe₂(SO₄)₃-containing brines and UV exposure under Mars analog conditions.
Medicinal plants: bioactive compounds, biological activities ... frontiersin.org 3 facts
claimPyrus salicifolia (willow-leaved pear), originating from Asia, demonstrated in vitro antimicrobial activities against Bacillus subtilis, Bacillus pumalis, Candida albicans, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus.
claimThe fruit extract of Cucurbita maxima (Buttercup squash) demonstrates antibacterial efficacy against Staphylococcus aureus, Bacillus subtilis, and Micrococcus luteus under laboratory conditions.
claimDioscorea bulbifera (air potato), originating from Tropical Africa and Asia, demonstrated in vitro antimicrobial activities against Bacillus subtilis, Bacillus pumalis, Candida albicans, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus.
Engineering biology applications for environmental solutions - Nature nature.com Apr 14, 2025 1 fact
claimHybrid engineered living materials (HELM) have facilitated the development of biocomposite thermoplastic polyurethanes embedded with Bacillus subtilis spores genetically tailored through adaptive laboratory evolution and synthetic biology techniques.