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axonal branching
Also known as: axonal branching points
Facts (10)
Sources
Branching morphology determines signal propagation dynamics in ... nature.com Aug 21, 2017 10 facts
accountThe study analyzed two basic units of neuronal branching trees: axonal linear segments and axonal branching points.
referenceStockbridge, N. and Stockbridge, L. L. analyzed the effect of electrotonic length on differential conduction at axonal bifurcations in a 1988 paper published in the Journal of Neurophysiology.
procedureIn the study of axonal branching, researchers induced current pulses at the upstream edge of the mother branch and measured the resulting responses along the two daughter branches.
referenceStockbridge, N. provided a theoretical basis for differential conduction at axonal bifurcations in a 1988 paper published in the Journal of Neurophysiology.
claimAction potential propagation fails at axonal branching points, leading to a blockage, when the geometric ratio exceeds a critical value that is dependent on temperature.
claimConduction block at axonal branching points can occur either sequentially in one branch before the other or simultaneously in both daughter branches.
claimAsymmetric responses in axonal branching points have been observed experimentally, though they previously lacked theoretical characterization.
measurementMeasurements of axonal branching points with two different radii showed that the two daughter branches exhibit different responses.
measurementHigh spatio-temporal multi-electrode arrays have been used to record differential modulation responses between axonal branches.
referenceThe study 'Branching morphology determines signal propagation dynamics in...' utilizes a spatial extension of the Hodgkin-Huxley model to systematically explore how geometrical parameters of axonal linear segments and axonal branching points affect neuronal electrophysiological activity patterns.