concept

antitumor agent

Also known as: anticancer activity, antitumor activity, anti-cancer activity, antitumor agent, anti-tumor activity

Facts (12)

Sources

Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us Journal of Food Science & Nutrition 2 facts

claimEugenol, ursolic acid, linalool, and isoeugenol exhibit anti-neoplastic and anticancer properties by restricting cancer cell growth through apoptosis induction, cellular blockade, and inhibition of DNA synthesis, specifically demonstrating cytotoxic activity against Michigan Cancer Foundation-7 cells.

referenceMurraya koenigii (L.) Spreng. contains the active compounds mahanimbine, girinimbine, mahanine, and murrayafoline, which exhibit anti-cancer activity by increasing the death of cancerous cells through proteasome inhibition, as reported by Samantha et al.

Advances in Pharmacognosy for Modern Drug Discovery and ... jbph.org Journal of Basic and Pharmaceutical Health 2 facts

referenceTaxol was isolated from Taxus brevifolia and identified as a novel antileukemic and antitumor agent.

claimAdriamycin is an antibiotic with antitumor activity, as documented by Arcamone F, Cassinelli G, Fantini G, et al. in a 1969 study published in Biotechnology and Bioengineering.

Medicinal plants: bioactive compounds, biological activities ... frontiersin.org Frontiers in Immunology 2 facts

referenceChinese medicine compounds exert anti-tumor effects by regulating immune cells in the tumor microenvironment, as reported in a 2021 study.

claimZingiber officinale (ginger), originating from Southeast Asia, demonstrated in vivo anti-tumor growth by penetrating the tumor site and presumably increasing the permeability and retention (EPR) impact.

Vernonia amygdalina: a comprehensive review of the ... frontiersin.org Frontiers 1 fact

claimPhytochemicals found in Vernonia amygdalina—specifically alkaloids, flavonoids, terpenoids, phenolics, and tannins—exhibit biological activities including antimicrobial effects, antioxidant properties, disease prevention and therapy, free radical scavenging, anticancer activity, and antiviral potential.

Phytobioactive compounds as therapeutic agents for human ... onlinelibrary.wiley.com Wiley Apr 17, 2023 1 fact

claimPolyphenols, alkaloids, terpenes, and polysaccharides isolated from medicinal plants exhibit antioxidant, anticancer, cytotoxic, and anti-inflammatory biological activities.

Wild edible plants for food security, dietary diversity, and nutraceuticals frontiersin.org Frontiers Nov 27, 2025 1 fact

referenceA study by Wang et al. (2023) identified a polysaccharide from Inula japonica that demonstrates in vivo antitumor activity by interacting with TLR-4, PD-1, and VEGF.

Active Plant Principles and Applications in Plant Medicine irispublishers.com Daniela Rebeca Ardelean, Ramona Stef, Monica Butnariu · Iris Publishers May 2, 2024 1 fact

claimSome volatile oils have demonstrated antitumor activity and insecticidal properties.

Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu International Academic Publishing House 1 fact

referenceFridlender, Kapulnik, and Koltai (2015) published 'Plant derived substances with anti-cancer activity: from folklore to practice' in Frontiers in Plant Science, discussing the transition of plant-derived substances from traditional use to clinical practice.

Cellular senescence: from homeostasis to pathological implications ... frontiersin.org Frontiers 1 fact

referenceRetinoic acid receptor activation reprograms the senescence response and enhances the anti-tumor activity of natural killer cells, as reported in a 2024 study in Cancer Cell.