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The cardiorespiratory response to exercise demonstrates hierarchical control of homeostatic regulation: the first level consists of tissues and organs of the cardiovascular and respiratory systems (heart, lung, blood vessels, kidneys, and endocrine glands); the second level consists of the baroreceptor and cardiorenal reflexes; and the third level of regulation occurs within the medulla (NTS) of the central nervous system where sensory information is processed and efferent responses are initiated.

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