In type 1 diabetes, hyperglycemia causes a paradoxical secretion of glucagon because the high glucose levels directly impair the activity of pancreatic alpha cells, an effect not accounted for in standard negative feedback models.

Authors

• Person: Not available Organization: Springer
  Homeostasis and Health: From Balance to Change | Biological Theory

Sources

• Homeostasis and Health: From Balance to Change | Biological Theory link.springer.com Springer via serper

Referenced by nodes (1)

• glucagon concept