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From a physicochemical and biochemical point of view, nervous tissue is peculiar, difficult material to investigate. The physico-chemical processes underlying production of an action potential occur within an extremely thin membrane structure and progress at a disturbingly high rate. Most of the chemists’ standard tools are totally inadequate to follow such rapid processes involving such a limited quantity of chemical substance in labile, “living” tissue. Only electronic devices employed by communication engineers have had the sensitivity and the rapidity to respond to the signs of physicochemical events taking place in the nerve membrane.

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