Psychedelic stimulation of 5-HT2A receptors increases the excitability of neocortical pyramidal neurons and augments extracellular glutamate release in the prefrontal cortex, which disrupts cortical rhythmicity and large-scale brain networks.

Authors

• Person: Not available Organization: Frontiers
  Psychedelics, Sociality, and Human Evolution

Sources

• Psychedelics, Sociality, and Human Evolution www.frontiersin.org Frontiers via serper

Referenced by nodes (3)

• 5-HT2A receptor concept
• prefrontal cortex concept
• glutamate concept