In an esophageal carcinoma tumor initiation model, a high-fat diet increases Lgr5+ progenitor cells and promotes tumor growth in mice with premalignant esophageal lesions, acting as a second hit to initiate tumors in situ.

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• Person: Not available Organization: Genes & Development
  Dietary interventions as regulators of stem cell behavior in ...

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• Dietary interventions as regulators of stem cell behavior in ... genesdev.cshlp.org Genes & Development via serper

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• high-fat diet concept