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The administration of L-Alpha-Aminoadipic Acid (L-AAA), an astrocyte-specific gliotoxin, intracerebroventricularly (i.c.v) reverses the protective effects of harmine on glial fibrillary acidic protein (GFAP) reduction in mice subjected to chronic unpredictable stress (CUS), suggesting that harmine's regulatory effects are mediated by astrocytic function (Liu et al. 2017).

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