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Several large epidemiological studies (Eaker et al., 1992; Qureshi et al., 1997; Schwartz et al., 1998; Newman et al., 2000; Ayas et al., 2003; et al., 2005; Bradley et al., 2005; Caples et al., 2005) and one case-control study (Liu et al., 2002) associate sleep loss and sleep complaints with heart attacks (myocardial infarction) and potentially stroke.

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