A small molecule cocktail (SMC) consisting of SB431542 (a TGFβ inhibitor), CHIR99021 (a GSK3β inhibitor), BIX01294 (an H3K9 methyltransferase/G9a inhibitor), and all-trans retinoic acid (ATRA) can cause liver cancer cells to lose their malignant phenotype and acquire hepatocyte properties.

Authors

• Person: Not available Organization: Nature
  Cellular rejuvenation: molecular mechanisms and potential ... - Nature

Sources

• Cellular rejuvenation: molecular mechanisms and potential ... - Nature www.nature.com Nature via serper

Referenced by nodes (1)

• liver cancer concept