During antibody-dependent cellular cytotoxicity, Natural Killer (NK) cells recognize target cells via IgG antibodies attached to the target cells through Fab regions, while the Fc portion of the IgG antibody engages the CD16 (Fc-gRIII) receptor on the NK cell, linking the two cells and inducing the apoptotic pathway.

Authors

• Person: Not available Organization: Immunopaedia
  3. The Innate Immune System - Immunopaedia

Sources

• 3. The Innate Immune System - Immunopaedia www.immunopaedia.org.za Immunopaedia via serper

Referenced by nodes (2)

• NK cells concept
• Natural killer (NK) cells concept