SASP inhibitors require continuous treatment to maintain suppression of the Senescence-Associated Secretory Phenotype (SASP), which increases the likelihood of side effects compared to the intermittent administration of senolytic drugs.

Authors

• Person: Not available Organization: Nature
  Cellular rejuvenation: molecular mechanisms and potential ... - Nature

Sources

• Cellular rejuvenation: molecular mechanisms and potential ... - Nature www.nature.com Nature via serper

Referenced by nodes (2)

• senolytics concept
• senescence-associated secretory phenotype concept