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related 3.70 — strongly supporting 12 facts
Multiple large-scale studies, including the Sleep Heart Health Study {fact:1, fact:9} and research by Bixler et al. {fact:10, fact:11, fact:12}, have established a strong clinical association between sleep-disordered breathing and hypertension. Furthermore, sleep-disordered breathing is recognized as a contributing factor to the development of hypertension due to its systemic effects on vascular tone and inflammatory mediators {fact:3, fact:4}.
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Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov 12 facts
claimA 2000 prospective study published in the New England Journal of Medicine established an association between sleep-disordered breathing and hypertension.
referenceBixler et al. (2000) investigated the association between hypertension and sleep-disordered breathing.
referenceBixler EO, Vgontzas AN, Lin HM, Ten Have T, Leiby BE, Vela-Bueno A, and Kales A studied the association of hypertension and sleep-disordered breathing, published in the Archives of Internal Medicine in 2000.
claimSleep-disordered breathing has been found in a high frequency of individuals with transient ischemic attacks (McArdle et al., 2003), hypertension (Morrell et al., 1999), myocardial infarction, and heart failure (Good et al., 1996; Shamsuzzaman et al., 2003).
claimNieto et al. (2000) identified an association between sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study known as the Sleep Heart Health Study.
claimSleep-disordered breathing and sleep apnea are associated with hypertension in community-based populations.
claimSleep-disordered breathing is found in a high frequency of individuals with hypertension.
claimRisk factors for stroke include heart disease, hypertension, alcohol abuse, transient ischemic attacks, and possibly sleep-disordered breathing, according to Diaz and Sempere (2004).
claimSleep-disordered breathing may contribute to the development of hypertension, coronary artery disease, congestive heart failure, arrhythmias, stroke, glucose intolerance, and diabetes.
referenceBixler, Vgontzas, Lin, Ten Have, Leiby, Vela-Bueno, and Kales found an association between hypertension and sleep-disordered breathing.
claimThe Sleep Heart Health Study, published in the Journal of the American Medical Association in 2000, found an association between sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study.
claimSystemic effects of sleep-disordered breathing, such as altered vascular tone, inflammatory mediator levels, and hormonal changes, may contribute to the development of hypertension, coronary artery disease, congestive heart failure, arrhythmias, stroke, glucose intolerance, and diabetes.