mast cells ↔ macrophages

Relations (1)

related 2.58 — strongly supporting 5 facts

Macrophages and mast cells are related as they both originate from the myeloid progenitor [1], [2], function as cytokine-releasing immune cells [3], [4], and complete their differentiation in tissues to act as effector cells in host defense [5].

Facts (5)

Sources

The components of the immune system - Immunobiology - NCBI - NIH ncbi.nlm.nih.gov Janeway CA Jr, Travers P, Walport M · Garland Science 3 facts

claimThe myeloid progenitor cell is the precursor for granulocytes, macrophages, dendritic cells, and mast cells of the immune system.

claimThe myeloid progenitor is the precursor cell type for granulocytes, macrophages, dendritic cells, and mast cells of the immune system.

claimMacrophages and mast cells complete their differentiation in tissues, where they function as effector cells in host defense and initiate inflammation.

Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US thermofisher.com Thermo Fisher Scientific 1 fact

claimIL-6 is produced by monocytes, fibroblasts, and endothelial cells, and upon stimulation, it is secreted by macrophages, T cells, B cells, mast cells, glial cells, eosinophils, keratinocytes, and granulocytes.

What are Cytokines? Types & Function - Cleveland Clinic my.clevelandclinic.org Cleveland Clinic 1 fact

claimImmune cells that release cytokines include macrophages, dendritic cells, lymphocytes (T and B lymphocytes), monocytes, neutrophils, basophils, eosinophils, and mast cells.