Knowledge Tree
Relations (1)
related 2.32 — strongly supporting 4 facts
Cortisol is explicitly identified as the major glucocorticoid [1] and a primary example of the steroid hormones known as glucocorticoids [2]. Furthermore, both are involved in the physiological stress response [3] and are subject to regulation by the enzyme 11β-HSD2 [4].
Facts (4)
Sources
Self-awareness, self-regulation, and self-transcendence (S-ART) frontiersin.org 1 fact
claimA decreased stress response and rapid return to physiological and emotional baseline involves physiological mediators including catecholamines (epinephrine and norepinephrine), glucocorticoids (cortisol), pituitary hormones (ACTH, prolactin, and growth hormones), and cytokines (IL-1, IL-6, and TNF-α).
Allostasis revisited: A perception, variation, and risk framework frontiersin.org 1 fact
claimThe enzyme 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) protects mineralocorticoid receptor-expressing tissues from glucocorticoid activation by breaking down corticosterone and cortisol.
Stress: Its Negative Impact on Your Mental & Physical Health cwcare.net 1 fact
claimThe activation of the hypothalamic-pituitary-adrenal (HPA) axis results in increased production of steroid hormones known as glucocorticoids, which include cortisol, commonly referred to as the “stress hormone.”
Systems and organs | Anatomy and Physiology | Research Starters ebsco.com 1 fact
claimCortisol, the major glucocorticoid, regulates the production and use of glucose, fats, and amino acids by cells and tissues.