Knowledge Tree
Relations (1)
related 0.30 — supporting 3 facts
The brain and immune system are interconnected as they jointly prompt energy shortages from chronic inflammation and aging [1], with the immune system overreacting in Alzheimer’s to damage the brain via inflammatory cytokines [2], and both undergoing aging processes like immunosenescence [3].
Facts (3)
Sources
A Double-Edged Sword: Inflammation and Your Health - Cedars-Sinai cedars-sinai.org 2 facts
claimIn Alzheimer’s disease, the immune system mistakenly targets plaques and tangles, causing it to overreact and release inflammatory cytokines that damage the brain.
quoteMaya Koronyo, PhD, stated: "With aging, our bodies undergo a process called immunosenescence, or aging of the immune system. So it's not only your brain and heart that are aging, and your skin that is wrinkling, but there's also a specific process that causes the immune cells to become less responsive and ultimately ineffective."
Effects of psychedelics on neurogenesis and broader neuroplasticity link.springer.com 1 fact
claimThe CB2 receptor is less prevalent in the brain but is widely expressed in the immune system, as noted by Onaivi (2006) and Pertwee (2006).