Relations (1)

related 3.00 — strongly supporting 7 facts

Heart rate and minute ventilation are both key cardiorespiratory variables recorded in studies of hypoxic stress [1] and are used together in multivariate models to predict changes in peripheral oxygen saturation {fact:2, fact:3} and energy expenditure [2]. Furthermore, their physiological responses are statistically correlated during hypoxic exercise, as demonstrated by polynomial regression analysis [3].

Facts (7)

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Sex differences in respiratory and circulatory cost during hypoxic ... nature.com Nature 6 facts
claimWhen using multiple regression to predict changes in energy expenditure (ΔEE), both changes in minute ventilation (ΔV̇E) and changes in heart rate (ΔHR) were statistically significant predictors for both men and women.
claimThe study used sex-specific models to analyze changes in energy expenditure (EE), minute ventilation (V̇E), and heart rate (HR), which resulted in similar changes for both men and women.
measurementA multivariate model using energy expenditure (EE), minute ventilation (V̇E), and heart rate (HR) to predict hypoxia-induced reduction in peripheral oxygen saturation (ΔSpO2) achieved a very strong fit for both men (r2 = 0.900, P < 0.001) and women (r2 = 0.957, P < 0.001).
claimThe relative contributions of energy expenditure (EE), minute ventilation (V̇E), and heart rate (HR) to hypoxia-induced reduction in peripheral oxygen saturation (ΔSpO2) differ between sexes, with the contribution of EE and V̇E in women being about two-fold higher than in men, while the contribution of HR in men is greater than in women.
measurementIn a study of sex differences in respiratory and circulatory cost during hypoxic walking, the correlation between changes in minute ventilation (ΔV̇E) and changes in heart rate (ΔHR) was analyzed using second-order polynomial regression, yielding an r2 of 0.718 for men and 0.615 for women.
procedureThe researchers calculated changes in SpO2 with hypoxia and used multiple regression analysis to test for the independent, additive effects of energy expenditure (EE), ({\dot{{\rm{V}}}}{{\rm{E}}}), and heart rate (HR) on SpO2 after logarithmic transformation.
Sex differences in cardiorespiratory control under hypoxia - Frontiers frontiersin.org Frontiers 1 fact
procedureThe experimental protocol for the study on sex differences in cardiorespiratory control under hypoxia involved recording hemodynamic variables (heart rate, stroke volume, cardiac output, blood pressure) and respiratory variables (breathing frequency, tidal volume, minute ventilation, SpO2) after a 20-minute rest period in a sitting position.