Relations (1)

Facts (3)

Sources
Neuroimaging in psychedelic drug development: past, present, and ... nature.com Nature 3 facts
claimFuture research in psychedelic therapy aims to address the relationship between acute drug effects and longer-term clinical effects, the characterization of 5-HT2A receptor effects, and the impact of these compounds on neuroplasticity.
claimClinical studies in psychedelic therapy aim to establish a 'molecular-functional-clinical bridge' by characterizing the relationship between acute and longer-term clinically-relevant effects, investigating the 5-HT2A receptor's association with functional and clinical effects, and focusing on neuroplasticity.
perspectiveThere is a prevailing scientific viewpoint that putative increases in neuroplasticity likely underlie the positive clinical effects of psychedelic therapy, a hypothesis largely derived from pre-clinical research.