Knowledge Tree
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related 4.17 — strongly supporting 17 facts
Rheumatoid arthritis is a primary example of an autoimmune disease that causes chronic inflammation by triggering a persistent immune attack on healthy joint tissues, as described in [1], [2], and [3]. This relationship is further supported by the fact that chronic inflammation is a central component of the pathophysiology and disease progression of rheumatoid arthritis [4], [5], and [6].
Facts (17)
Sources
What Is Inflammation? Types, Causes & Treatment my.clevelandclinic.org 4 facts
claimIn rheumatoid arthritis, inflammatory cells and substances attack joint tissues, leading to chronic inflammation that comes and goes and can cause severe damage to the joints.
claimRheumatoid arthritis is an example of chronic inflammation where inflammatory cells and substances attack joint tissues, leading to inflammation that comes and goes and causes severe joint damage.
claimChronic inflammation is involved in the disease process of autoimmune diseases (lupus, rheumatoid arthritis, psoriasis, ankylosing spondylitis), cardiovascular diseases (heart disease, high blood pressure), certain cancers, gastrointestinal diseases (Crohn’s disease, inflammatory bowel disease), lung diseases (asthma, chronic obstructive pulmonary disease), mental health conditions (depression, anxiety), metabolic diseases (Type 2 diabetes), and neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease).
claimIn rheumatoid arthritis, the immune system continues to send inflammatory cells and substances to attack joint tissues even when there is no danger, leading to chronic inflammation that causes severe joint damage.
Chronic Inflammation - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov 4 facts
claimChronic inflammation can arise from recurrent episodes of acute inflammation, though in some cases, such as tuberculosis and rheumatoid arthritis, it is an independent response rather than a sequel to acute inflammation.
claimAutoimmune disorders cause chronic inflammation when the immune system recognizes normal body components as foreign antigens and attacks healthy tissue, leading to diseases such as rheumatoid arthritis and systemic lupus erythematosus.
claimInadequately treated rheumatoid arthritis, where chronic inflammation persists in the synovium, is associated with a worse prognosis and radiographic disease progression.
claimChronic inflammation in rheumatoid arthritis is induced in genetically susceptible hosts by environmental factors such as smoking and infections, leading to a systemic autoimmune response and local joint inflammation.
What causes chronic inflammation, and why it matters health.osu.edu 4 facts
claimDiseases such as diabetes, prolonged infections, and autoimmune diseases like rheumatoid arthritis can cause chronic inflammation by keeping the immune system in a persistent attack mode.
claimIf autoimmune diseases such as lupus or rheumatoid arthritis cause chronic inflammation, medications to lower the immune system response may be required.
procedureTreating chronic inflammation involves identifying and addressing the underlying cause of the immune system's overactivity, such as removing toxins like tobacco smoke or alcohol, treating chronic infections like hepatitis C or cancer, or using medications to lower immune system activity in cases of autoimmune diseases like lupus or rheumatoid arthritis.
claimIf chronic inflammation is caused by an autoimmune disease such as lupus or rheumatoid arthritis, treatment may require medications to lower immune system activity.
Inflammation bioxpedia.com 1 fact
claimChronic inflammation is associated with various diseases, including rheumatoid arthritis, inflammatory bowel disease (IBD), dermatological diseases, cardiovascular diseases, neurological diseases, diabetes, and several types of cancer.
What is Inflammation? Causes, Effects, Treatment - Harvard Health health.harvard.edu 1 fact
claimAutoimmune diseases, including type 1 diabetes, rheumatoid arthritis, lupus, psoriasis, inflammatory bowel disease, and multiple sclerosis, are known to cause chronic inflammation.
Inflammation: Types, symptoms, causes, and treatment medicalnewstoday.com 1 fact
claimChronic inflammation may increase the risk of various diseases, including some cancers, rheumatoid arthritis, atherosclerosis, periodontitis, and hay fever.
The Role of Immune Cells in Inflammation jmolpat.com 1 fact
claimChronic inflammation is implicated in the pathophysiology of atherosclerosis, rheumatoid arthritis, inflammatory bowel disease, and cancer.
Chronic Inflammation: How to Test For it and Prevent it medichecks.com 1 fact
claimChronic inflammation is associated with various conditions, including autoimmune diseases (thyroid conditions, rheumatoid arthritis), cardiovascular diseases (high blood pressure, heart disease), gastrointestinal disorders (inflammatory bowel disease, Crohn's disease, ulcerative colitis), lung diseases (COPD, asthma), mood conditions (depression), metabolic diseases (type 2 diabetes), neurodegenerative diseases (Parkinson’s disease), and some cancers.