Knowledge Tree
Relations (1)
related 0.40 — supporting 4 facts
Lymphocytes mediate inflammation by secreting cytokines, costimulating other lymphocytes, and producing antibodies [1], and are recruited to sites of injury or infection during the acute phase of inflammation [2]. In chronic inflammation, lymphocytes replace neutrophils alongside macrophages [3], while CXC chemokines facilitate their homing to inflammation sites [4].
Facts (4)
Sources
Chronic Inflammation - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov 2 facts
claimLymphocytes, including T-lymphocytes and B-lymphocytes, mediate inflammation by secreting cytokines, costimulating other lymphocytes, and producing antibodies and immune complexes.
claimDuring the progression of inflammation from acute to chronic, the composition of white blood cells changes as macrophages and lymphocytes replace short-lived neutrophils.
Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US thermofisher.com 1 fact
claimCXC chemokines are primarily involved in recruiting immune cells to sites of inflammation and mediating homeostatic migration and homing of lymphocytes.
The Role of Immune Cells in Inflammation jmolpat.com 1 fact
claimAs the acute phase of inflammation progresses, monocytes, lymphocytes, and eosinophils are recruited to the site of injury or infection.