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Inflammation produces TNF-α, a key cytokine that activates endothelial cells lining blood vessels, resulting in increased vascular permeability and immune cell recruitment [1].

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Sources
The Role of Immune Cells in Inflammation jmolpat.com Lukas Freund · Journal of Molecular Pathophysiology 1 fact
claimTumor Necrosis Factor-alpha (TNF-α) is a key cytokine produced during inflammation that activates endothelial cells lining blood vessels, leading to increased vascular permeability and the recruitment of additional immune cells to the site of inflammation.